6-溴-3H-咪唑并[4,5-B]嘧啶-2甲醇

6-溴-3H-咪唑并[4,5-B]嘧啶-2甲醇 - Names and Identifiers

Name	(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol
Synonyms	(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl) 6-Bromo-3H-imidazo[4,5-b]pyridine-2-methanol 6-Bromo-1H-imidazo[4,5-b]pyridine-2-methanol 3H-Imidazo[4,5-b]pyridine-2-methanol, 6-bromo- 3H-imidazo[4,5-b]pyridine-2-methanol, 6-bromo- (6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol (6-bromo-3H-imidazo[4,5-b]pyridin-2-yl)methanol (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol 6-Bromo-2-(hydroxymethyl)-3H-imidazo[4,5-b]pyridine
CAS	172648-19-0
InChI	InChI=1/C7H6BrN3O/c8-4-1-5-7(9-2-4)11-6(3-12)10-5/h1-2,12H,3H2,(H,9,10,11)

6-溴-3H-咪唑并[4,5-B]嘧啶-2甲醇 - Physico-chemical Properties

Molecular Formula	C7H6BrN3O
Molar Mass	228.05
Density	1.927g/cm³
Melting Point	230-233℃
Boling Point	463.55°C at 760 mmHg
Flash Point	234.147°C
Vapor Presure	0mmHg at 25°C
Storage Condition	2-8°C
Sensitive	IRRITANT
Refractive Index	1.763
MDL	MFCD09750272

6-溴-3H-咪唑并[4,5-B]嘧啶-2甲醇 - Introduction

(6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol is an organic compound with the chemical formula C9H5BrN2O. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: yellow or brown solid powder.
-Solubility: Soluble in common organic solvents (such as ethanol, ether and dichloromethane).
-Melting point: About 220-225 ℃.
-Stability: relatively stable under regular conditions.

Use:
- (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol is an important intermediate compound that can be used in organic synthesis and pharmaceutical research.

Method:
The preparation of- (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol usually involves a multi-step reaction. A common synthetic method is to react 2-bromo-6-aminoimidazo [4,5-b] Pyrimidine with a certain brominating agent (such as N-bromosuccinimide), then it is treated with alkaline solution to obtain 6-bromo-3H-imidazo [4,5-b] pyrimidine, and finally the target product (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol is obtained by reduction.

Safety Information:
- (6-bromo-1H-imidazo[4,5-b]pyridin-2-yl)methanol should be used and stored in accordance with general laboratory safety procedures.
-The compound may be irritating to the eyes, skin and respiratory system, so wear appropriate personal protective equipment such as goggles, gloves and lab coats during operation.
-Avoid inhaling the dust or gas of the substance, and avoid direct contact with skin, eyes, etc.
-If you are exposed to this substance, immediately rinse the affected area with plenty of water and seek medical help.
-During storage, the substance should be stored in a sealed container, away from heat and fire sources, and avoid contact with oxidants and strong acids.

Last Update：2024-04-09 20:49:11